Deferiprone

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
 
  • Liver disease, such as liver failure, hepatitis, or cirrhosis
  • Kidney disease, such as kidney failure (renal failure)
  • Low potassium levels (hypokalemia)
  • Low magnesium levels (hypomagnesemia)
  • Congestive heart failure (CHF)
  • A slow heart rate (bradycardia)
  • QT prolongation or long QT syndrome
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
 
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Deferiprone to learn more, including information on who should not take the drug.)
 

How Does It Work?

Deferiprone is an iron chelator. This means that it binds with iron in the blood, allowing it to be excreted through the urine; normally, iron cannot be excreted through the urine. Thus, using deferiprone helps to lower levels of iron in the blood.
 

Clinical Effects of Deferiprone

This medication has been extensively evaluated in clinical studies. These studies evaluated deferiprone in people who did not adequately respond to other iron chelation therapies. In these studies, about half of the people had a "good response" to the drug, meaning these people had at least a 20 percent reduction in iron levels within the first year of use.
 

Deferiprone Drug Information

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