Deferiprone Side Effects

Although it can be difficult to predict whether someone will develop side effects with deferiprone, clinical studies have shown that nausea, vomiting, and joint pain are some of the most commonly reported problems. It is also common for the urine to turn dark reddish-brown. However, seek immediate medical treatment if you develop potentially serious problems like an irregular heart rhythm or signs of an infection.

An Introduction to Side Effects of Deferiprone

Just like any medicine, deferiprone (Ferriprox®) can cause side effects. However, not everyone who takes the drug will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with deferiprone. Your healthcare provider can discuss a more complete list with you.)
 

Deferiprone Side Effects to Report

Some side effects of deferiprone are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
 
  • An irregular heart rhythm (arrhythmia)
 
  • Any sign of an infection, such as a sore throat or fever (deferiprone can cause dangerously low white blood cell levels, increasing the risk for serious infections)
 
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
 
Your healthcare provider should regularly monitor your white blood cell counts using a simple blood test. Liver enzymes (which can sometimes increase) and zinc levels (which can sometimes decrease) should also be monitored.
 

Deferiprone Drug Information

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