Drug Interactions With Deferiprone

Milk thistle, zinc, and products that contain calcium or magnesium can cause problems when used in combination with deferiprone. Drug interactions such as these may change how your body absorbs deferiprone, potentially making it less effective or increasing your risk for side effects. Make sure your healthcare provider has a current list of all medicines, vitamins, or supplements you are taking.

An Overview of Deferiprone Interactions

Deferiprone (Ferriprox®) can potentially react with a few other medications. Some of the products that may lead to drug interactions with deferiprone include but are not limited to:
 
  • Products that contain calcium or magnesium, including many supplements, antacids, and laxatives
  • Clobazam (Onfi™)
  • Eltrombopag (Promacta®)
  • Iron
  • Milk thistle
  • Zinc, including many cold/cough products.
 

More Information on Drug Interactions With Deferiprone

The following sections explain in detail the potentially negative interactions that can occur when deferiprone is combined with any of the drugs listed above.
 
Calcium or Magnesium
Calcium and magnesium can bind to deferiprone, preventing it from being absorbed from the digestive tract and making it less effective. Do not take deferiprone and calcium or magnesium within four hours of each other.
 
Clobazam
Clobazam may increase the level of deferiprone in the blood, increasing the risk for deferiprone side effects. Check with your healthcare provider before taking these medications together.
 
Eltrombopag
Eltrombopag may increase the level of deferiprone in the blood, increasing the risk for side effects. Check with your healthcare provider before taking these medications together.

Deferiprone Drug Information

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