Diseases Home > Autoimmune Disorder Symptoms

Autoimmune diseases occur when the immune cells in your body mistake your body's cells as invaders and attack them. In most cases, the first autoimmune disorder symptoms are fatigue, muscle aches, and low fever. Other common autoimmune disorder symptoms include underactive thyroid, overactive thyroid, lupus, multiple sclerosis, and rheumatoid arthritis.

Autoimmune Disorder Symptoms: An Overview

Autoimmune disorder symptoms can affect almost any organ or body system. In fact, there are more than 80 types of autoimmune diseases. The exact problem one has with an autoimmune disorder will depend on which tissues are targeted. In many people, the first symptoms of an autoimmune disorder are fatigue, muscle aches, and low fever.

Common Autoimmune Disorder Symptoms

Being able to recognize the symptoms of some of the more common autoimmune disorders can help people seek proper treatment early. However, some autoimmune disorders share similar symptoms, which makes it hard for doctors to make a diagnosis. Some of the common autoimmune disorder symptoms include:
Hashimoto's Thyroiditis (Underactive Thyroid)
For this type of autoimmune disorder, symptoms can include:
  • Tiredness
  • Depression
  • Sensitivity to cold
  • Weight gain
  • Muscle weakness and cramps
  • Dry hair
  • Tough skin
  • Constipation.
However, sometimes there are no symptoms.
Graves' Disease (Overactive Thyroid)
For this type of autoimmune disorder, symptoms can include:
  • Insomnia (unable to sleep)
  • Irritability
  • Weight loss without dieting
  • Heat sensitivity
  • Sweating
  • Fine, brittle hair
  • Muscle weakness
  • Unusually light menstrual periods
  • Bulging eyes
  • Shaky hands.
However, sometimes there are no symptoms.
Written by/reviewed by:
Last reviewed by: Arthur Schoenstadt, MD
Last updated/reviewed:
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