Diseases Home > Rilonacept

Rilonacept is a drug used to treat hereditary autoinflammatory conditions in adults and children as young as 12 years old. Specifically, rilonacept is used to treat a group of rare conditions called cryopyrin-associated periodic syndromes (CAPS), including familial cold autoinflammatory syndrome and Muckle-Wells syndrome. It comes as an injection that is given once a week. Side effects include coughing and reactions at the injection site.

What Is Rilonacept?

Rilonacept (Arcalyst®) is a prescription medication approved to treat cryopyrin-associated periodic syndromes (CAPS) in adults and children as young as 12 years old. CAPS are a rare hereditary group of autoinflammatory conditions, including familial cold autoinflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS).
 
(Click What Is Rilonacept Used For? for more information on this topic, including possible off-label uses.)
 

Are There Side Effects?

Just like any medicine, rilonacept may cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
 
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
 
Common rilonacept side effects include but are not limited to:
 
  • Reactions at the injection site, such as redness, swelling, itching, or bruising
  • Upper respiratory tract infections
  • Coughing
  • Reduced sensitivity to touch.
 
(Click Rilonacept Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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