Diseases Home > What Is Sine Scleroderma?

Sine Scleroderma
Some doctors break systemic scleroderma down into a third subset called sine (Latin for "without"). Sine resembles limited or diffuse systemic sclerosis, causing changes in the lungs, kidneys, and blood vessels. However, there is one key difference between sine and other forms of systemic sclerosis: it does not affect the skin.
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Last reviewed by: Arthur Schoenstadt, MD
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