Diseases Home > Side Effects of Tdap
Although most people respond well to Tdap, side effects are possible. In clinical studies, the most common problems that were reported with this vaccine included headache, fatigue, and injection site swelling, pain, or redness. While side effects of the vaccine are often mild, you should seek medical attention immediately if you experience a high fever, severe arm swelling, or any behavior changes.
- Severe shoulder and/or upper arm pain (which may be a sign of a problem known as brachial neuritis)
- Severe arm swelling
- Weakness, tingling, or paralysis (which may be signs of Guillain-Barré syndrome)
- A high fever
- Any behavior changes
- Signs of an allergic reaction, such as:
- An unexplained rash
- Swelling of the mouth or throat
- Difficulty breathing.