Diseases Home > Tdap Dosage

For most people, the recommended dose of the Tdap vaccine is one 0.5 mL vaccine injected a single time in people ages 10 and up. This is ideally given between the ages of 11 and 12. Although there is only one standard dosage, different factors will influence the timing of your vaccination (such as your age and previous vaccination history).

Tdap Dosage: An Introduction

There is only one standard dosage for Tdap (Adacel®, Boostrix®), although it can be confusing to know when exactly (or if) the vaccine should be given. The following factors will influence the timing of the vaccine:
  • Your previous vaccination history
  • Your age
  • Whether or not you have been exposed to pertussis.

Tdap Dosing Recommendations

Adacel is approved for people 11 to 64 years of age; Boostrix is approved for people ages 10 and older.
The standard Tdap dosage is one vaccine (0.5 mL) injected a single time in individuals ages 10 and up. Ideally, this will be given between the age of 11 and 12, although Tdap can be given at any time as long as at least five years have passed since the previous Td (tetanus and diphtheria) booster was given.
In some cases, at the healthcare provider's discretion, Tdap can be given sooner than five years. For instance, if you have been exposed to pertussis, your healthcare provider may decide to give Tdap even if it has not been five years since your last Td.
It is recommended that women receive Tdap immediately after giving birth (if they have not already received the Tdap vaccine earlier), in order to prevent the spread of pertussis to the newborn, as long as at least two years have passed since the previous Td booster.
After being vaccinated with Tdap, it is recommended that people continue to receive the Td vaccine every 10 years (as was previously recommended). Essentially, Tdap replaces one of the Td boosters (for most people).
Although most people should receive only one dose of Tdap (either Boostrix or Adacel), there is one exception. Pregnant women should receive a dose with each pregnancy, even if they have received the vaccine previously. This will help protect the newborn from pertussis. Ideally, it should be given any time between 27 and 36 weeks of pregnancy, although it can be given any time. If a woman chooses not to get the vaccine during pregnancy, it is recommended that she receive it immediately after giving birth. 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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