Rilonacept Mechanism of Action

Rilonacept (Arcalyst®) is a medication used to treat a rare group of symptoms that cause inflammation in the body. Specifically, the drug is used to treat familial cold autoinflammatory syndrome (FCAS) and Muckle-Wells syndrome (MWS), both of which belong to a group of hereditary autoinflammatory conditions called cryopyrin-associated periodic syndromes (CAPS). This prescription drug is an interleukin-1 beta (IL-1β) blocker. But how does rilonacept work?
Rilonacept works by blocking the actions of interleukin-1 beta (IL-1β), a certain protein of the immune system that causes inflammation in the body. People with CAPS have increased levels of IL-1β, which leads to inflammation in the body. By blocking the action of IL-1β, rilonacept reduces inflammation and symptoms associated with CAPS.
(For more information on this medication and its mechanism of action, click Rilonacept. This article provides a complete overview of the drug, including information on its uses, general precautions, and potential side effects.)
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