Rilonacept Use in Rheumatoid Arthritis

Rilonacept (Arcalyst®) is approved for the treatment of rare autoinflammatory conditions called cryopyrin-associated periodic syndromes (CAPS). However, there are also some "off-label," or unapproved, uses for this drug.
For example, a healthcare provider may sometimes prescribe rilonacept for use in the treatment of rheumatoid arthritis. Off-label use is when a drug is used in a way that has not been officially approved by the U.S. Food and Drug Administration (FDA). It is also sometimes called an "unapproved" or "nonapproved" use. Off-label use is legal, and many medicines are used appropriately and safely for off-label purposes.
Rilonacept works by blocking the action of a certain protein in the body that causes inflammation.
(For more details on this drug's off-label uses, click What Is Rilonacept Used For?. This Web selection also describes how the medication works, who can use it, and more.)
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