More Info on Rilonacept Indications

How Does This Medication Work?

Rilonacept works by blocking the actions of interleukin-1 beta (IL-1β), a protein of the immune system that causes inflammation in the body. People with CAPS have increased levels of IL-1β, which leads to inflammation in the body. By blocking the action of IL-1β, rilonacept reduces the inflammation and symptoms associated with CAPS.

Can Children Use Rilonacept?

Rilonacept is approved for use in children who are at least 12 years old. It has not been adequately studied in younger children.
In animal studies, the drug altered fetal bone development when given to pregnant monkeys. It is unknown whether the medication will also affect bone development in children. Therefore, it is recommended that children who use rilonacept be monitored for appropriate growth.

Is It Safe for Older Adults?

There were not enough older adults in rilonacept clinical trials to say for certain that older adults will respond to this drug in the same way as younger age groups. In general, older adults may have an increased risk for certain rilonacept side effects and may need more careful monitoring.

Are There Reasons to Use Rilonacept Off-Label?

On occasion, a healthcare provider may recommend this medication for something other than the conditions discussed in this article. This is called an "off-label" use. Rilonacept may be used off-label for the treatment of gout and rheumatoid arthritis.
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Rilonacept Drug Information

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