The group of diseases we call scleroderma fall into two main types: localized scleroderma and systemic scleroderma (also known as systemic sclerosis). Each type of scleroderma has subtypes.
Subtypes of localized scleroderma include morphea and linear scleroderma. Subtypes of systemic scleroderma include limited scleroderma, diffuse scleroderma, and sine scleroderma.
Although scientists do not know the exact cause of scleroderma, they are certain that people cannot catch it from or transmit it to others. Studies also show that scleroderma is not inherited.
Scientists suspect that scleroderma is the result of several factors, which may include:
Abnormal immune or inflammatory activity
Genetics
Environment
Hormones.
(Click Scleroderma Causes for more information about factors that may play a role in the development of the disorder.)
What Is Scleroderma? -- Symptoms
Symptoms of scleroderma will depend on the type and subtype of scleroderma that a person has. However, in most patients, early include swelling and puffiness of the fingers or hands and Raynaud's phenomenon (a disorder that affects the blood vessels in the fingers, toes, ears, and nose).
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