Sjogren's Syndrome and Lymphoma

Although it is uncommon, a small percentage of people develop both Sjogren's syndrome and lymphoma. However, whereas in most cases of lymphoma, the lymph nodes in the neck, underarm, or groin are affected, in Sjogren's syndrome, lymphoma often involves the salivary glands. Treatment options for people with Sjogren's syndrome and lymphoma will vary for each person.

Sjogren's Syndrome Complications

Sjogren's Syndrome and Lymphoma: An Overview

About 5 percent of people with Sjogren's syndrome develop cancer of the lymph nodes (lymphoma). The most common symptom of lymphoma is a painless swelling of the lymph nodes in the neck, underarm, or groin. In Sjogren's syndrome, when lymphoma develops, it often involves the salivary glands. Persistent enlargement of the salivary glands should be investigated further.

Other symptoms may include the following:

Unexplained fever
Night sweats
Constant fatigue
Unexplained weight loss
Itchy skin
Reddened patches on the skin.

However, these symptoms are not sure signs of lymphoma. They may be caused by other, less serious conditions, such as the flu or an infection. If you have these symptoms, see a doctor so that any illness can be diagnosed and treated as early as possible.

If you're worried that you might develop lymphoma, talk to your doctor to learn more about the disease, symptoms to watch for, any special medical care you might need, and what you can do to relieve your worry.