Drugs That React With Tdap

Tdap Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Tdap is combined with any of the drugs listed above.
 
Immunosuppressant Medications
If you are taking an immunosuppressant, you may not receive the full benefit of Tdap for protection from tetanus, diphtheria, and pertussis (whooping cough). With some vaccines (especially live vaccines), people taking immunosuppressants may be at a higher risk of actually developing the infection (usually a mild form) from the vaccine. However, because Tdap is not a live vaccine, this is not a problem.
 
Other Vaccines
Studies indicate that giving Tdap at the same time as the influenza vaccine ("flu shot") might slightly reduce the effectiveness of Tdap. Giving Tdap with the hepatitis B vaccine does not seem to interfere with either of the vaccines. Tdap has not been studied in combination with any other vaccines.
 
If other vaccines are given at the same time, different syringes and different injection sites must be used. Tdap should not be combined with any other vaccines in the same syringe.
 
Tetanus Immune Globulin
If Tdap and tetanus immune globulin must be given at the same time, they should be given with different syringes and needles at different parts of the body.
 

Final Thoughts

It is possible that not all drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions with Tdap that may apply to you.
 
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